Formulas · Clear Heat 淸熱 · Gogeum Uigam (古今醫鑑)

Augmented Six-to-One Powder

Gamiyugil-san

한글 가미육일산  ·  Pinyin Jia Wei Liu Yi San

加味六一散

The base is the two-drug summerheat powder registered as igwon-san, which the Bogam gives under four names — 益元散, 六一散, 天水散 and 神白散 — talc and licorice in the six-to-one ratio that the second name states. This leaf is that base with cinnabar and borneol added, and is a formula in its own right rather than a second citation of it.

Composition 構成

Total 277.2 g per packet (첩) · representative dosage — verify against source texts. Excludes 1 ingredient measured by count or used as a vehicle, shown as —.

Received this formula from your practitioner? Amounts shown here are classical reference values — granule and prepared products differ. Always follow your prescribed dosage and directions.

Actions 效能

Indications 主治

Pattern-based

  • Heat toxin too abundant (熱毒太盛) with raving and thirst
  • Pox red and purple, black and sunken (痘瘡紅紫黑䧟)

Biomedical correlates

  • Haemorrhagic smallpox — historical management
  • Confluent smallpox
  • Fever with dehydration in a child

Source text 原文

Donguibogam 東醫寶鑑

治熱毒太盛, 狂言煩渴, 及痘瘡紅紫黑䧟. 滑石 六兩(硏水飛), 甘草細末 六錢, 辰砂(水飛) 三錢, 片腦 三分(另硏別入). 右和勻, 春秋以燈心煎湯調下, 夏月以新汲水調下. 三五歲兒服一錢, 十歲服二錢. 發熱之初, 用<a href='/formulas/gamipaedok-san-soa'>加味敗毒散</a>調下, 能解毒稀痘, 出痘紅紫者亦效. 《醫鑑》

Translation

Treats heat toxin at its height with wild speech and vexed thirst, and pox gone red and purple or black and sinking. Talc, 6 nyang, ground and water-levigated; finely powdered licorice, 6 don; cinnabar, water-levigated, 3 don; borneol, 3 fun, ground apart and put in separately. Mix the above evenly; in spring and autumn give it stirred into a juncus decoction, in the summer months stirred into newly drawn water. A child of three to five years takes 1 don, a ten-year-old 2 don. At the onset of fever, give it washed down with Gamipaedok-san, and it can resolve the toxin and thin the pox; where the pox has come out red and purple it is also effective. — Uigam 醫鑑 (Donguibogam · Soa)

Clinical commentary 臨床

The six-to-one powder with two things added, and the indication is the one that mattered. 紅紫 is an eruption gone dark and purplish and running together rather than standing as discrete firm pocks; 黑䧟, black sinking, is haemorrhagic smallpox — bleeding into the skin and into the pocks, a flat dusky rash that fails to raise. Those were the two signs that genuinely predicted death. Discrete smallpox killed about one in ten; confluent smallpox killed well over half; the haemorrhagic form killed very nearly everyone who had it, usually before the pustular stage was reached. A tradition that put both at the head of a formula's indication, beside raving and thirst, was reading the right signs off the right patient. The two parts of the formula pull in opposite directions. Talc and licorice stirred into newly drawn water is, in effect, a cool drink with a bland diuretic in it, and the thirst and the raving in a child with a confluent eruption are fluid loss — the one thing modern care would have corrected with nothing more than fluid. That part of the prescription was not useless. The additions were. **Contains cinnabar, which is mercuric sulfide — mercury. There is no safe dose at any age, the developing nervous system is the organ at risk, and the injury does not reverse; the full statement is on jinsa-go-soa. Unusually for this chapter this leaf does give a dose by age: 1 don for a child of three to five, 2 don for a ten-year-old. Cinnabar is 3 don in a batch weighing a little over 277 g, so about one part in twenty-three by weight — roughly 0.17 g of mercuric sulfide in each dose given to a three-year-old, repeated. This must not be prepared.** — Eui Young (Justin) Chung, L.Ac., Dipl. O.M.

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